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Answer
Important factors to consider when deciding when or if to use ovulation
inducing medications are your age, the amount of time you have been trying
to get pregnant, and what the reasons may be that you are having difficulty
getting pregnant.
Women who do not ovulate on their own are very appropriate candidates
for using these medications, even without a very comprehensive
infertility evaluation. On the other hand, if you are ovulating fine
and your doctor is putting you on the medication to produce more eggs
and therefore possibly increase your chance to get pregnant, you should
have a thorough evaluation prior to using these medications. In the
right situations they can significantly improve your chance to get
pregnant.
The ovulation inducing medications do, however, have potential side
effects. For the medication Clomiphene these include twins, ovarian
cysts, nausea, bloating, hot flashes, blurred vision and mood changes.
For the fertility injections (gonadotropins) potential side effects
include multiple pregnancy, and ovarian overstimulation
(hyperstimulation).
There is some controversy as to whether taking ovulation inducing
medications can increase a woman's risk of developing ovarian cancer.
Most studies that have evaluated this have not found an increased risk,
however a couple of controversial studies have suggested that there may
be an increased risk in women who take ovulation inducing medication
who have never used birth control pills ( birth control pills are
protective against ovarian cancer) and who never get pregnant in their
lifetime (pregnancy is protective). Though most experts feel that there
is little if any increased risk, it may be years before we have the
final answer. It therefore seems prudent to only use these medications
when indicated, and under proper supervision. They should also not be
used for many months, but if you do not get pregnant after three or so
months of use, you and your physician should reevaluate what may be
your best course of action.
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